Which of the following statements regarding complement is FALSE?
A)Certain complement proteins are always circulating in the blood in an inactive state.
B)Activated complement can form a membrane attack complex,which forms pores in microbe membranes.
C)Activated complement can stimulate cells to secrete inflammation-mediating chemicals.
D)The complement pathway is always dependent upon activation of the first complement protein,C1.
E)Some activated complement proteins activate other complement proteins.

Question

Which of the following statements regarding complement is FALSE?
A)Certain complement proteins are always circulating in the blood in an inactive state.
B)Activated complement can form a membrane attack complex,which forms pores in microbe membranes.
C)Activated complement can stimulate cells to secrete inflammation-mediating chemicals.
D)The complement pathway is always dependent upon activation of the first complement protein,C1.
E)Some activated complement proteins activate other complement proteins.

Quizplus · Accepted Answer

The complement pathway has multiple activation pathways, including the classical pathway (dependent upon C1 activation), the alternative pathway, and the lectin pathway. Therefore, the complement pathway is not always dependent upon activation of the first complement protein, C1.

Which of the Following Statements Regarding Complement Is FALSE