Which applies to the classical complement pathway,but NOT to the alternative complement pathway?
A)Activation of C3 results in the formation of C3b.
B)There is a cascade of proteins activated,which results in the killing of microbes.
C)Complement proteins serve as opsonins that facilitate phagocyte binding to microbes.
D)Antibodies activate the first complement protein (C1).
E)Complement activation leads to the development of a multiunit protein called the membrane attack complex (MAC).

Question

Quizplus · Accepted Answer

Antibodies activate the classical complement pathway by binding to the first complement protein, C1. This does not occur in the alternative complement pathway, which is activated by microbial surfaces directly interacting with complement proteins.

Which Applies to the Classical Complement Pathway,but NOT to the Alternative