The body's first line of defense against invasion by microbes are physical and chemical barriers.

Name: The body's first line of defense against invasion by microbes are physical and chemical barriers.
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The body has physical barriers such as skin, mucous membranes, and cilia, as well as chemical barriers such as stomach acid and antimicrobial substances in tears and sweat, that serve as the first line of defense against invading microbes.

The Body's First Line of Defense Against Invasion by Microbes