Camryn Has Had Dozens of Mosquito Bites This Summer

Camryn has had dozens of mosquito bites this summer.She is trying an antihistamine cream in large quantities this week and finds that she rarely itches at all.Should she be concerned about this use?

A) Yes,prolonged use of topical antihistamines can cause tolerance and even dependence.
B) Yes,prolonged use of topical antihistamines can cause hypersensitivity reactions.
C) No,over-the-counter topical antihistamines do not have any known adverse effects.
D) Probably not,as long as there is also an antibiotic and a corticosteroid in the cream.