If a prodrug's active metabolite produced antidepressant effects,then:
A) the prodrug is also an antidepressant drug.
B) the active metabolite could be likely be directly administered as an antidepressant drug.
C) the prodrug had acted like a placebo.
D) the prodrug was unable to cross the blood-brain barrier.

Question

Quizplus · Accepted Answer

If the prodrug's active metabolite produced antidepressant effects, it indicates that the active metabolite has pharmacological activity and can be used as an antidepressant drug. Therefore, the active metabolite could likely be directly administered as an antidepressant drug. The prodrug itself may or may not have antidepressant activity, but it serves the purpose of delivering the active metabolite to the site of action.

If a Prodrug's Active Metabolite Produced Antidepressant Effects,then