When an agonist binds to a G-protein coupled receptor:
A) a G-protein repels away neurotransmitters.
B) neurotransmitters enter the neuron.
C) no effects occur for a G-protein.
D) a G-protein becomes activated.

Question

Quizplus · Accepted Answer

When an agonist binds to a G-protein coupled receptor, a conformational change in the receptor occurs, which activates the associated G-protein. This, in turn, initiates a signal transduction pathway leading to various cellular responses. Therefore, the correct choice is D - a G-protein becomes activated. None of the other options provide a proper explanation of what happens when an agonist binds to a G-protein coupled receptor.

When an Agonist Binds to a G-Protein Coupled Receptor