A 22 year old woman returned to the United States from a trip to Mexico.She suddenly became ill,with nausea and vomiting.She underwent a needle biopsy of the liver.Later,serology was found to be positive for hepatitis A virus.A representative section of her liver biopsy is shown in the accompanying photomicrograph.Which one of the following interpretations of the eosinophilic bodies denoted by the arrows marked "C" is most likely CORRECT?

Question

Quizplus · Accepted Answer

The pink bodies are apoptotic bodies,sometimes called Councilman bodies (after the American pathologist who first discovered them in the liver of patients with yellow fever).As you recall,apoptosis is individual cell death,signalled,in this case,by T cells responding to hepatocytes expressing viral antigen on their cell surfacEThus,it is an indirect effect of the virus.

A 22 Year Old Woman Returned to the United States