A 50 year old man was brought to the Emergency Department in a stupor by police.A history was unobtainable.An initial workup disclosed jaundice,elevated liver function tests,and a blood alcohol of 300 mg/dL (the legal limit is 80 mg/dL).In order to ascertain the extent of his liver problem,a needle biopsy of the liver was performed.A representative section of the biopsy is shown in the accompanying photomicrograph.Which one of the following is the most likely composition of the eosinophilic cytoplasmic substance labelled "H" in the high power view of the biopsy shown on the right?

Question

Quizplus · Accepted Answer

The structure is called Mallory's or "alcoholic" hyalinEElectron microscopy and immunohistochemical stains have identified this substance as condensed cytokeratin intermediate filaments.

A 50 Year Old Man Was Brought to the Emergency