A 28 year old woman with a 7 year history of Systemic Lupus Erythematosus was experiencing increasing BUN and creatinine levels.Her physicians recommended a renal biopsy,a representative section of which is shown in the accompanying photomicrograph.Which one of the following is the best diagnosis?

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Membranous nephropathy can present on its own (85% of cases)or in combination with Lupus Erythematosus,in which case it is classified as WHO Lupus Class V nephropathy.The glomerular cellularity is not apparently increased,but increased deposition of basement membrane due to "dense deposits" of antigen-antibody complexes gives the characteristic "wire loop" appearancE

A 28 Year Old Woman with a 7 Year History