Entry of the poliovirus genome into the host cell involves all of the following EXCEPT…

Question

Quizplus · Accepted Answer

Poliovirus entry into the host cell does not require acidification of the endosome. This step is characteristic of some other viruses that rely on endosomal acidification to trigger fusion with the host cell membrane or conformational changes necessary for genome release. Poliovirus entry involves receptor binding, conformational changes, and the extrusion of VP1 N-terminus and loss of VP4, but not endosomal acidification.

Entry of the Poliovirus Genome into the Host Cell Involves