In the picornavirus genome, there are several A nucleotides found at the 3' end of both the positive and negative sense strands.How are these A nucleotides used in replication of the RNA genome?

Question

Quizplus · Accepted Answer

The A nucleotides at the 3' end of both strands of picornavirus genome basepair with the U nucleotide bound to the viral protein VPg during replication. This allows the RNA-dependent RNA polymerase to initiate RNA synthesis and complete the synthesis of the full-length genome.

In the Picornavirus Genome, There Are Several a Nucleotides Found