Since flaviviruses replicate in the cytoplasm of the host cell, they do not need to encode a methyltransferase enzyme to produce the 5' cap on the viral genomic RNA.

Question

Quizplus · Accepted Answer

Flaviviruses do need to encode a methyltransferase enzyme to produce the 5' cap on the viral genomic RNA, as this is required for efficient translation of the viral proteins.

Since Flaviviruses Replicate in the Cytoplasm of the Host Cell