When a Client Is Diagnosed with Schizophrenia and Asks What

When a client is diagnosed with schizophrenia and asks what could have caused the disorder,the statements that could serve as a basis for answering include which of the following? (Select all that apply.)

A) Schizophrenia may be related to abnormal cerebral structure.
B) Schizophrenia is inherited as an autosomal recessive gene defect.
C) Schizophrenia often develops in the absence of family psychopathology.
D) Chronic prolonged stress may contribute to development of schizophrenia.
E) Symptoms of schizophrenia may be associated with smoking.