Select the statements that are true regarding the initiation of DNA replication in bacteria.
A) It involves a region of the DNA called oriC.
B) Proteins bind to the DNA to begin separation of the strands.
C) The strands are initially separated at GC-rich regions of DNA.
D) Following initial separation, DNA helicase enzymes continue to separate the strands.

Question

Quizplus · Accepted Answer

A) It involves a region of the DNA called oriC: This is true. The initiation of DNA replication in bacteria starts at a specific region of the DNA called oriC, which serves as the recognition site for the replication machinery.
B) Proteins bind to the DNA to begin separation of the strands: This is true. Proteins (such as DnaA and DNA helicase) bind to the oriC region of the DNA and start the process of unwinding the strands by separating them at the AT-rich regions.
C) The strands are initially separated at GC-rich regions of DNA: This is not true. The strands are initially separated at AT-rich regions of DNA, not GC-rich regions.
D) Following initial separation, DNA helicase enzymes continue to separate the strands: This is true. After the initial separation of the strands, DNA helicase continues to separate the strands as the replication fork moves along the DNA.

Select the Statements That Are True Regarding the Initiation of DNA