Prevents supercoiling ahead of the replication fork.
A) DNA ligase
B) DNA primase
C) Topoisomerase
D) DNA polymerase I
E) DNA polymerase III

Question

Quizplus · Accepted Answer

Topoisomerases are responsible for preventing supercoiling ahead of the replication fork by breaking and rejoining the DNA strands, allowing them to rotate and relieve tension. DNA ligase joins Okazaki fragments, DNA primase synthesizes RNA primers, DNA polymerase I is involved in the removal of RNA primers and the filling of gaps, and DNA polymerase III is responsible for the majority of DNA synthesis during replication.

Prevents Supercoiling Ahead of the Replication Fork