Which of the following statements is true concerning the use of cyclic di-GMP as a second messenger?
A) It activates the expression of flagellin genes and thus enhances motility.
B) It is found in all microbes: bacteria, archaea, and eukaryotic microbes.
C) It is produced by the action of diguanylate cyclase.
D) It decreases in level as biofilm is produced.
E) Phosphodiesterase can convert GMP to cyclic di-GMP.

Question

Quizplus · Accepted Answer

Cyclic di-GMP is produced by the action of diguanylate cyclase (DGC). It is a common second messenger in bacteria and regulates a variety of processes, including biofilm formation, motility, virulence, and cell cycle progression. It is not found in all microbes, and its level increases as biofilm is produced. Phosphodiesterase converts cyclic di-GMP to GMP, not the other way around.

Which of the Following Statements Is True Concerning the Use