The Patient's Rheumatoid Arthritis Symptoms Were Not Adequately Controlled with Methotrexate

The patient's rheumatoid arthritis symptoms were not adequately controlled with methotrexate so adalimumab was prescribed as well.What is the rationale for prescribing both medications?

A) To obtain a synergistic effect
B) To prevent an anaphylactic reaction
C) To reduce medication interactions
D) To avoid an iosyncratic reaction