Calculate the pH at the isoelectric point for a 0.10 M solution of the amino acid threonine.pK_a1 = 2.088 and pK_a2 = 9.100 for threonine.

Question

Quizplus · Accepted Answer

Threonine has two ionizable groups, with pK values of 2.088 and 9.100. At the isoelectric point, the amino acid is in its zwitterionic form, where the positive and negative charges cancel out. This occurs when the pH is equal to the average of the pK values:

(pK1 + pK2)/2 = (2.088 + 9.100)/2 = 5.594

Therefore, the pH at the isoelectric point for threonine is approximately 5.59.

Calculate the PH at the Isoelectric Point for a 0