As an investigator you want to functionally inactivate a gene without altering its sequence.Which of the following would you use to accomplish this?
A)gene knockout
B)RNA interference
C)dominant negative mutation
D)RNA interference and dominant negative mutation

Question

Quizplus · Accepted Answer

RNA interference (RNAi) and dominant negative mutations are techniques used to functionally inactivate a gene without altering its DNA sequence. RNAi works by degrading mRNA or blocking its translation, while dominant negative mutations produce a protein that interferes with the function of the wild-type protein.

As an Investigator You Want to Functionally Inactivate a Gene