Protein kinase A is converted from an inactive state to an active state by binding:
A)ATP.
B)calcium.
C)cAMP.
D)ATP and cAMP.

Question

Quizplus · Accepted Answer

Protein kinase A is activated by binding to the molecule cAMP. This binding causes a conformational change that activates the enzyme, allowing it to phosphorylate its target proteins. ATP is used as a substrate for the kinase to transfer phosphate to its target protein, but it is not necessary for the activation of the enzyme. Calcium is not directly involved in the activation of protein kinase A. Therefore, the best choice is C, cAMP.

Protein Kinase a Is Converted from an Inactive State to an Active