You are studying the effects of α-amanitin,a poisonous cyclic octapeptide,on eukaryotic cells and have noticed that following treatment,there is no miRNA transcription.Based on this evidence you conclude that α-amanitin must be inhibiting:
A)RNA polymerase I.
B)RNA polymerase II.
C)RNA polymerase III.
D)RNA polymerase I and RNA polymerase III.

Question

Quizplus · Accepted Answer

miRNA transcription is primarily mediated by RNA polymerase II. Therefore, the inhibition of miRNA transcription by α-amanitin suggests that this toxin is specifically targeting RNA polymerase II.

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