What is the function of TFIIH in the transcription initiation complex?
A)binding to the TATA box
B)unwinding the DNA duplex
C)catalyzing the synthesis of RNA
D)all of the above

Question

Quizplus · Accepted Answer

TFIIH is responsible for unwinding the DNA duplex, which is necessary for the transcription process. It also has helicase and kinase activities and is involved in phosphorylation of RNA polymerase II, which is required for initiation of transcription. It does not directly bind to the TATA box or catalyze RNA synthesis.

What Is the Function of TFIIH in the Transcription Initiation