Which of the following is true about ER import?
A) N-terminal signal sequences have been determined to be necessary for ER import because if they are added to sequences which are not normally targeted to the ER,they will end up in the ER.
B) Signal recognition particles (SRPs) are needed during co-translational import.
C) Ribosomal translation of a 6-12 amino acid sequence on the N-terminus will initiate the process through interactions with SRP.
D) GTP hydrolysis by the Sec61 translocon causes ribosomal translation to begin again after it is halted by SRP binding.
Correct Answer:
Verified
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