Which of the following are enzyme pairs that catalyze opposite reactions?
A)MEK and MAP kinase
B)NF-B and I-B
C)PI-3 kinase and PTEN phosphatase
D)JAKs and STATs
E)none of the above

Question

Quizplus · Accepted Answer

PI-3 kinase and PTEN phosphatase catalyze opposite reactions in the phosphoinositide 3-kinase (PI3K) signaling pathway. PI-3 kinase adds a phosphate group to phosphatidylinositol (4,5)-bisphosphate (PIP2) to generate phosphatidylinositol (3,4,5)-trisphosphate (PIP3), while PTEN removes the phosphate group from PIP3 to regenerate PIP2. The other enzyme pairs listed do not catalyze opposite reactions.

Which of the Following Are Enzyme Pairs That Catalyze Opposite