Which protein stabilizes an intermediate in the Ras GTP hydrolysis reactions?
A)Sos
B)GRB2
C)RTK
D)Raf

Question

Quizplus · Accepted Answer

Sos (Son of Sevenless) is a guanine nucleotide exchange factor that stabilizes the intermediate in the Ras GTP hydrolysis reaction by catalyzing the exchange of GDP for GTP on Ras. This leads to the activation of downstream signaling pathways. GRB2 (Growth Factor Receptor-bound protein 2), RTK (Receptor Tyrosine Kinase), and Raf (Rapidly Accelerated Fibrosarcoma) are also involved in the Ras signaling pathway but do not directly stabilize the intermediate in the GTP hydrolysis reaction.

Which Protein Stabilizes an Intermediate in the Ras GTP Hydrolysis