All genes regulated by PKA contain a cis-acting DNA sequence that binds to the phosphorylated form of a transcription factor called:
A)β-catenin.
B)CREB.
C)c-Jun.
D)TCF.

Question

Quizplus · Accepted Answer

Genes regulated by PKA contain a cis-acting DNA sequence called the cAMP response element (CRE), which binds to the phosphorylated form of the transcription factor CREB (cAMP response element binding protein). Therefore, the correct choice is B, CREB. The other options (A) β-catenin, (C) c-Jun, and (D) TCF, are transcription factors that are not specifically associated with PKA-mediated gene regulation.

All Genes Regulated by PKA Contain a Cis-Acting DNA Sequence