During mitosis,the breakdown of the nuclear envelope depends on the:
A)disassembly following proteasomal degradation of intermediate filaments.
B)disassembly of lamin filaments following phosphorylation by mitotic cyclin/cdk complexes.
C)ubiquitination of mitotic cyclin proteins.
D)lamin filament dephosphorylation by cdc14.

Question

Quizplus · Accepted Answer

The breakdown of the nuclear envelope during mitosis requires the disassembly of lamin filaments, which make up the nuclear lamina. The disassembly is triggered by phosphorylation of lamin filaments by mitotic cyclin/cdk complexes. This phosphorylation weakens the interactions between the lamin filaments, leading to their disassembly and breakdown of the nuclear envelope.

During Mitosis,the Breakdown of the Nuclear Envelope Depends on The