In a Type II hypersensitivity reaction,when mismatched blood is administered causing an ABO incompatibility,what destroys the erythrocytes?

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In a Type II hypersensitivity reaction due to ABO incompatibility, the antibodies bind to the antigens on the erythrocytes, leading to complement activation and subsequent cell lysis. This is known as complement-mediated cell lysis. Phagocytosis by macrophages and natural killer cells are more commonly seen in Type III and Type IV hypersensitivity reactions, respectively. Phagocytosis in the spleen may also occur, but it is not the primary mechanism of erythrocyte destruction in ABO incompatibility.

In a Type II Hypersensitivity Reaction,when Mismatched Blood Is Administered