What is the consequence for cells when the functioning p53 gene is lost due to mutation?

Question

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The functioning of the p53 gene is to prevent cells from dividing when there is DNA damage. It does so by either stopping the cell cycle to allow for DNA repair or inducing apoptosis (programmed cell death) if the damage is too severe. When the gene is lost due to mutation, cells can escape apoptosis and continue to divide even with damaged DNA, leading to the potential development of cancer.

What Is the Consequence for Cells When the Functioning P53