What Causes the Macrovascular Complications of Clients with Diabetes Mellitus

What causes the macrovascular complications of clients with diabetes mellitus?

A) The capillaries contain plaques of lipids that obstruct blood flow.
B) There is increased pressure within capillaries caused by the elevated glucose attracting water.
C) The capillary basement membranes thicken and there is endothelial cell hyperplasia.
D) Fibrous plaques form from the proliferation of subendothelial smooth muscle of arteries.