How is glucose 6-phosphate dehydrogenase (G-6-PD)inherited?
A) As an X-linked dominant disorder
B) As an X-linked recessive disorder
C) As an autosomal dominant disorder
D) As an autosomal recessive disorder

Question

Quizplus · Accepted Answer

Glucose 6-phosphate dehydrogenase deficiency is inherited as an X-linked recessive disorder, meaning that the gene responsible for producing the enzyme is located on the X chromosome. Males only have one X chromosome, so if they inherit the mutated gene, they will develop the condition. In females, who have two X chromosomes, the mutation must be present on both chromosomes to be expressed, but carriers of the mutation can still be affected by some symptoms.

How Is Glucose 6-Phosphate Dehydrogenase (G-6-PD)inherited