How is hemoglobin S (HbS) formed in sickle cell disease?
A) By a deficiency in glucose 6-phosphate dehydrogenase (G-6-PD) that changes hemoglobin A to hemoglobin S
B) By a genetic mutation in which two amino acids (histidine and leucine) are missing
C) By a genetic mutation in which one amino acid (valine) is replaced by another (glutamic acid)
D) By an autoimmune response in which one amino acid (proline) is detected as an antigen by abnormal immunoglobulin G (IgG)
Correct Answer:
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