Which immunoglobulins may contribute to the pathophysiology of asthma?
A) Immunoglobulin A
B) Immunoglobulin E
C) Immunoglobulin G
D) Immunoglobulin M

Question

Quizplus · Accepted Answer

Immunoglobulin E (IgE) is the immunoglobulin responsible for the immune response in asthma. When allergens are inhaled, they trigger the production of IgE, which then binds to receptors on mast cells and basophils. When these cells encounter the allergen again, the IgE-bound cells release inflammatory mediators, such as histamine, leading to bronchoconstriction and asthma symptoms.

Which Immunoglobulins May Contribute to the Pathophysiology of Asthma