Considering the pathophysiology of osteoporosis,what are the effects of extracellular signal regulated kinases (ERKs)and receptor activator of nuclear factor _kß ligand (RANKL)on osteoblasts and osteoclasts? A) ERKs increase the life span of osteoclasts and RANKL decreases the life span of osteoblasts. B) ERKs and RANKL increase the life span of osteoclasts and decrease the life span of osteoblasts. C) ERKs and RANKL increase the life span of osteoblasts and decrease the life span of osteoclasts. D) ERKs increase the life span of osteoblasts and RANKL decreases the life span of osteoclasts.

Question

Quizplus · Accepted Answer

Extracellular signal regulated kinases (ERKs) and receptor activator of nuclear factor _kß ligand (RANKL) increase the life span of osteoclasts and decrease the life span of osteoblasts. This leads to a net decrease in bone mass and density, which is characteristic of osteoporosis. Therefore, option B is the correct answer.

Considering the Pathophysiology of Osteoporosis,what Are the Effects of Extracellular