Consider the transplantation of tissue from a donor to a recipient who has a different HLA type but the same ABO blood type.Why will the recipient be likely to reject a kidney from the donor,but will not reject the blood from the donor?

Question

Quizplus · Accepted Answer

Red blood cells do not have Class I MHC molecules, which identify foreign cells to the immune system. Therefore, the recipient will not recognize the donor's blood as foreign and will not mount an immune response. However, kidney tissue does have Class I MHC molecules, and the recipient's immune system will recognize the donor's kidney tissue as foreign and launch an attack.

Consider the Transplantation of Tissue from a Donor to a Recipient