During a Major Infection a Fever Often Develops

During a major infection a fever often develops.What best explains the origin of this change in body temperature?

A) The infectious pathogens produce chemicals that stimulate the brain to elevate the temperature,creating an environment more suitable to bacterial growth.
B) The immune system stimulates the brain to elevate the temperature,an action that both limits bacterial growth and increases the rate of phagocytosis.
C) The infectious pathogens damage tissues throughout the body,creating a negative thermoregulatory feedback cycle.
D) The subsequent low energy levels that result from the metabolic demands of fever impair the nervous system and disable the homeostatic system that controls body temperature.