In the early 1980s,a number of clones encoding highly-related forms of actin were isolated from a human cDNA library.Given the information that (i)the restriction enzyme maps of the coding regions were dissimilar,and (ii)each clone contained sufficient coding region to encode all or most of an entire actin gene,you would conclude that
A)multiple actin genes arose as a result of a segmental duplication.
B)the various forms of actin are a result of alternative splicing.
C)actin proteins are encoded by genes found in a tandem cluster.
D)actin proteins are encoded by a multigene family.

Question

Quizplus · Accepted Answer

The dissimilar restriction enzyme maps suggest that the clones are not the result of segmental duplication, and the fact that each clone contains most of the coding region of an entire actin gene suggests that they are not the result of alternative splicing. Therefore, the most likely explanation is that the clones are from a multigene family encoding highly-related forms of actin.

In the Early 1980s,a Number of Clones Encoding Highly-Related Forms