What is the likely consequence of a mutation in a point mutation affecting a branch point?
A)no effect,since branch points are located in introns
B)a splicing error
C)failure of snRNAs to recognize 5' end of intron
D)no exon shuffling

Question

Quizplus · Accepted Answer

Branch points are crucial for the proper splicing of pre-mRNA, and a point mutation affecting the branch point could lead to splicing errors. This can result in aberrant transcripts and potentially lead to disease if critical parts of the gene are affected. The other choices are incorrect - branch points are located in introns, but mutations can still affect them; snRNAs recognize the branch point, not the 5' end of the intron; and exon shuffling is not directly related to branch points.

What Is the Likely Consequence of a Mutation in a Point