In Drosophila,dosage compensation is controlled by the male-specific lethal (MSL)complex consisting of MSL proteins and roX RNAs.Based on what you know about dosage compensation,the role of the MSL complex would be to
A)increase the level of expression on the X chromosome approximately 2 fold.
B)increase the level of expression on the X chromosome approximately 50%.
C)decrease the level of expression on the X chromosome approximately 2 fold.
D)decrease the level of expression on the X chromosome approximately 50%.

Question

Quizplus · Accepted Answer

Dosage compensation is the mechanism by which organisms balance the expression of genes on sex chromosomes that exist in different copy numbers between males and females. In Drosophila, females have two X chromosomes while males have one X chromosome and one Y chromosome. To compensate for this difference in gene copy number, the MSL complex increases the level of expression of genes on the X chromosome in males approximately two-fold. Therefore, choice A is the best answer.

In Drosophila,dosage Compensation Is Controlled by the Male-Specific Lethal (MSL)complex