A deletion of a particular stretch of chromosome 15 can cause either Prader-Willi syndrome or Angelman syndrome,depending on
A)the parental origin of the normal and deleted chromosome.
B)whether or not the region is methylated properly.
C)whether a translocation event has occurred.
D)whether a nondisjunction event has occurreD.

Question

Quizplus · Accepted Answer

The deletion of a particular stretch of chromosome 15 can cause either Prader-Willi syndrome or Angelman syndrome, depending on the parental origin of the normal and deleted chromosome. This is due to genomic imprinting, where certain genes are expressed differently depending on which parent they are inherited from. Therefore, the same deletion can have different effects depending on whether it is on the maternal or paternal chromosome.

A Deletion of a Particular Stretch of Chromosome 15 Can