You have been asked to provide genetic counseling to a family who has a very high incidence of various types of cancer.After some discussion,you tell them that you will do some genetic testing to determine if they carry any mutations that predispose them to cancer.Mutations in which of following proteins are most commonly associated with cancers?
A)Ras and p53
B)Ras and Scr
C)Scr and Rb
D)Rb and p53

Question

Quizplus · Accepted Answer

Mutations in Rb (retinoblastoma) and p53 (tumor protein 53) are most commonly associated with cancers. Rb is a tumor suppressor protein that helps in regulating cell division and p53 is also a vital tumor suppressor protein that guards the cell from genetic mutations. Mutations in these genes can increase the likelihood of cancer occurrence. Ras and Scr are also known to be associated with cancer, but they are not as commonly implicated as Rb and p53.

You Have Been Asked to Provide Genetic Counseling to a Family