A mutation that affects Ca⁺⁺ binding to calmodulin is most likely to interfere with which aspect of a signal transduction pathway? A)the flow of Ca⁺⁺ ions through ion channel receptors B)the cellular response to the second messenger C)MAP kinase cascade D)G protein activity

Question

Quizplus · Accepted Answer

Ca⁺⁺ binding to calmodulin is an important step in the activation of various enzymes and cellular responses to second messengers. Therefore, a mutation that affects this binding is most likely to interfere with the cellular response to the second messenger. It is less likely to affect ion channel receptors, MAP kinase cascade, or G protein activity directly.

A Mutation That Affects Ca++ Binding to Calmodulin Is Most

A Mutation That Affects Ca⁺⁺ Binding to Calmodulin Is Most