If the effector protein phospholipase C failed to cleave phosphatidylinositol-4,5-bisphosphate (PIP₂),the action of which of the following molecules would be affected? A)cAMP B)calmodulin C)protein kinase A (PKA) D)protein kinase C (PKC)

Question

Quizplus · Accepted Answer

Phospholipase C cleaves PIP2 into inositol-1,4,5-trisphosphate (IP3) and diacylglycerol (DAG), which then activates protein kinase C. Therefore, if phospholipase C fails to cleave PIP2, the action of protein kinase C would be affected.

If the Effector Protein Phospholipase C Failed to Cleave Phosphatidylinositol-4,5-Bisphosphate