Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format.
An 18-month-old male is admitted to the hospital with symptoms of a respiratory infection. The patient’s mother reports that since birth, the toddler has frequently had a cough and copious nasal secretions. His weight gain has been poor, despite adequate oral intake. The patient appears in moderate respiratory distress, so oxygen therapy and IV fluids are initiated. The physician orders tests for cystic fibrosis due to the patient’s history and clinical presentation. When the tests confirm the diagnosis, as the RN, you provide education to the mother regarding this autosomal recessive disease.
-Which of the following terms would best describe a mutation that leads to the deletion of two bases from a DNA sequence?

Question

Please read the clinical scenario, and then answer the question that follow to become familiar with the traditional NCLEX question format.
  An 18-month-old male is admitted to the hospital with symptoms of a respiratory infection. The patient’s mother reports that since birth, the toddler has frequently had a cough and copious nasal secretions. His weight gain has been poor, despite adequate oral intake. The patient appears in moderate respiratory distress, so oxygen therapy and IV fluids are initiated. The physician orders tests for cystic fibrosis due to the patient’s history and clinical presentation. When the tests confirm the diagnosis, as the RN, you provide education to the mother regarding this autosomal recessive disease.
-Which of the following terms would best describe a mutation that leads to the deletion of two bases from a DNA sequence?

Quizplus · Accepted Answer

A frame shift mutation refers to an insertion or deletion of one or more nucleotides that changes the reading frame of a gene, resulting in a completely different amino acid sequence downstream of the mutation. In this scenario, the mutation involves the deletion of two bases from a DNA sequence, causing a frame shift mutation.

Please Read the Clinical Scenario, and Then Answer the Question