Norepinephrine and epinephrine open ____ channels inducing a faster diastolic depolarization.

Question

Quizplus · Accepted Answer

HCN channels, also known as hyperpolarization-activated cyclic nucleotide-gated channels, are responsible for the pacemaker potentials in the heart. Norepinephrine and epinephrine, by activating beta-adrenergic receptors, lead to an increase in cyclic AMP, which directly opens HCN channels. This results in a faster diastolic depolarization, contributing to an increased heart rate.

Norepinephrine and Epinephrine Open ____ Channels Inducing a Faster Diastolic