The idea that femaleness is simply what happens when an embryo does not develop as a male is no longer supported by evidence because of the discovery of

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The discovery of genes whose expression is necessary for female structures to develop, such as the Wnt4 gene, has challenged the idea that femaleness is simply the default state of an embryo in the absence of male development. This supports the idea that female development is an active process, rather than a passive one.

The Idea That Femaleness Is Simply What Happens When an Embryo