A healthy man and a healthy woman have a son with Lesch-Nyhan syndrome,an X-linked recessive trait.What are the chances that a daughter of this couple will inherit Lesch-Nyhan syndrome?

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Lesch-Nyhan syndrome is an X-linked recessive disorder, meaning that the gene causing the disorder is located on the X chromosome. Females inherit two X chromosomes, while males inherit one X chromosome and one Y chromosome. In order for a female to express Lesch-Nyhan syndrome, she would need to inherit the affected X chromosome from both parents. However, since neither parent is affected, they cannot pass on the affected X chromosome to their daughter. Therefore, the daughter has no chance of inheriting Lesch-Nyhan syndrome.

A Healthy Man and a Healthy Woman Have a Son