The following sequence is part of a genome.

C T G T G G T A A C T G A G T C A C T A G

Fragments corresponding to it that would be useful in deriving the sequence are
A) $G U C U C \quad G A U C \quad A C C A U \quad A U U G A \quad G A C U C \quad C U C A G \quad A G U G $
B) $ C TGTG \quad CTAG \quad TGGTA \quad TAACT \quad CTGAG \quad GAGTC \quad TCAC $
C) $CACT \quad CTGAG \quad GAGTC \quad TCAAT \quad ATGGT \quad GATC \quad GTGTC $
D) $ACG \quad GTGAT \quad CTGTA \quad CTGTGTAC \quad GTG \quad CTGACTG $
E) $ CTGATGT \quad CGTGT \quad CTGTGATGC \quad CGTGTA \quad CCCGTA $

Question

The following sequence is part of a genome.

C T G T G G T A A C T G A G T C A C T A G

Fragments corresponding to it that would be useful in deriving the sequence are
A) $G U C U C \quad   G A U C  \quad  A C C A U \quad  A U U G A  \quad  G A C U C  \quad  C U C A G  \quad   A G U G $
B) $  C TGTG \quad  CTAG \quad  TGGTA  \quad TAACT   \quad  CTGAG  \quad   GAGTC  \quad  TCAC $
C) $CACT \quad   CTGAG \quad   GAGTC \quad  TCAAT \quad  ATGGT \quad  GATC  \quad   GTGTC  $
D) $ACG \quad GTGAT   \quad   CTGTA   \quad CTGTGTAC \quad GTG  \quad  CTGACTG $
E) $ CTGATGT  \quad  CGTGT  \quad   CTGTGATGC  \quad  CGTGTA \quad  CCCGTA $

Quizplus · Accepted Answer

The fragments should be at least 5-10 nucleotides long and overlap enough to reconstruct the entire sequence. Based on this criteria, fragment set B is the best choice as the fragments overlap and cover the entire sequence without any gaps. Fragment sets A, C, D, and E do not provide enough coverage or overlapping to reconstruct the entire sequence.

The Following Sequence Is Part of a Genome GUCUCGAUCACCAUAUUGAGACUCCUCAGAGUGG U C U C \quad G A U C \quad A C C A U \quad A U U G A \quad G A C U C \quad C U C A G \quad A G U G GUCUCGAUCACCAUAUUGAGACUCCUCAGAGUG

The Following Sequence Is Part of a Genome $G U C U C \quad G A U C \quad A C C A U \quad A U U G A \quad G A C U C \quad C U C A G \quad A G U G$