The type of DNA repair that corrects errors due to oxidative damage by replacing one to five nucleotides is
A) mismatch repair.
B) base excision repair.
C) roto-rooter repair.
D) photoreactivation.
E) repair of the sugar-phosphate backbone.

Question

Quizplus · Accepted Answer

Base excision repair is the type of DNA repair that corrects errors due to oxidative damage by replacing one to five nucleotides. It involves the removal of a damaged base by a DNA glycosylase enzyme, followed by the cleavage of the sugar-phosphate backbone by an AP endonuclease, and the insertion of the correct nucleotide by a DNA polymerase and ligation by a DNA ligase. Mismatch repair corrects errors due to replication errors, photoreactivation repairs UV-induced damage, and repair of the sugar-phosphate backbone addresses breaks in the backbone. Roto-rooter repair is not a recognized type of DNA repair.

The Type of DNA Repair That Corrects Errors Due to Oxidative