Imprinting affects the phenotype when

Question

Quizplus · Accepted Answer

Imprinting only affects the phenotype when one allele is imprinted and the other is inactivated or deleted. This is because imprinting involves the selective silencing of one copy of a gene, which can result in different expression of the gene depending on which allele is silenced. If both alleles are imprinted, the phenotype would be affected, but not in the same way as when only one allele is imprinted and the other is inactivated or deleted. Similarly, exposure to methyl groups or having two female or two male genomes can also affect gene expression, but these do not involve imprinting specifically.

Imprinting Affects the Phenotype When